Potentially limiting their appeal even further, it now appears that statins, meant to lower your cholesterol, may blunt your desire to exercise and significantly limit the way your body responds to exercise. Statins are one … continue reading
Running does not cause arthritis. This is actually not a new finding. Researchers have know for years that running will not cause arthritis. Runners in general have a much lower chance of developing osteoarthritis than … continue reading
Rotator cuff surgery involves a long recovery process. Trust me… it is a lot longer than you think it will be. Depending on your occupation and the type of work you perform the recovery from … continue reading
The peroneal nerve is a large nerve that starts from behind your knee and travels down the outer side of your leg. The peroneal nerve sits close to a bone we call the fibula neck. … continue reading
Cartilage regeneration has been a focus of Orthopedic Surgeons for decades. Cartilage damage or defects can occur after an injury such as an ACL tear. Cartilage has proven to be a very difficult tissue to work … continue reading
There are very few runners who are satisfied with their race times. Many are “training” … but as we know, most runners will not train properly. Most focus solely on running, and then mostly on … continue reading
A broken tibia is not common in sports. But a tibia fracture can be a very severe and very painful injury that must be managed correctly if the athlete wishes to return to sports. Those of us … continue reading
Since the 1950s when it was invented, a cortisone shot has been used to treat many painful joint and tendon overuse injuries. Cortisone is a potent anti-inflammatory. People now receive a cortisone shot for tendon … continue reading
Mayo Clinic finds surprising results on first-ever test of stem cell therapy to treat arthritis.
JACKSONVILLE, Fla. — Researchers at Mayo Clinic’s campus in Florida have conducted the world’s first prospective, blinded and placebo-controlled clinical study to test the benefit of using bone marrow stem cells, a regenerative medicine therapy, to reduce arthritic pain and disability in knees.
The researchers say such testing is needed because there are at least 600 stem cell clinics in the U.S. offering one form of stem cell therapy or another to an estimated 100,000-plus patients, who pay thousands of dollars, out of pocket, for the treatment, which has not undergone demanding clinical study.
The findings in The American Journal of Sports Medicine include an anomalous finding — patients not only had a dramatic improvement in the knee that received stem cells, but also in their other knee, which also had painful arthritis but received only a saline control injection.
Each of the 25 patients enrolled in the study had two bad knees, but did not know which knee received the stem cells.
Given that the stem cell-treated knee was no better than the control-treated knee — both were significantly better than before the study began — the researchers say the stem cells’ effectiveness remains somewhat uninterpretable.
They are only able to conclude the procedure is safe to undergo as an option for knee pain, but they cannot yet recommend it for routine arthritis care.
“Our findings can be interpreted in ways that we now need to test — one of which is that bone marrow stem cell injection in one ailing knee can relieve pain in both affected knees in a systemic or whole-body fashion,” says the study’s lead author, Shane Shapiro, M.D., a Mayo Clinic orthopedic physician.
“One hypothesis is that the stem cells we tested can home to areas of injury where they are needed, which makes sense, given that stem cells injected intravenously in cancer treatments end up in the patients’ bone marrow where they need to go,” he says.
“This is just a theory that can explain our results, so it needs further testing.” Another explanation is that merely injecting any substance into a knee offered relief from pain.